4 articles • Revolutionary imaging techniques and applications
Revolutionary imaging techniques using DNA-barcoded conjugates, signal amplification methods, and high-resolution spatial analysis for advanced multiplexed protein detection.
Nuclear imaging presents unique challenges in spatial biology. Learn how left-handed DNA (L-DNA) oligonucleotide conjugates overcome nuclear membrane barriers for improved imaging.
Advances in spatial proteomics have underscored the need for highly multiplexed imaging platforms that can preserve tissue integrity while enabling comprehensive protein analysis.
Imaging Mass Cytometry (IMC) has the potential to profile ~40 proteins in tissues but struggles to detect low-abundance markers. The latest advance—SABER-IMC (Signal Amplification By Exchange Reaction for IMC).
In the evolving field of biomarker discovery and spatial biology, IN-situ DEtailed Phenotyping To High Resolution (IN-DEPTH) represents a groundbreaking approach for high-dimensional cellular analysis.
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