Should We Barcode All Research Antibodies with Oligos?
Exploring the potential and challenges of universal antibody barcoding with oligonucleotides for research applications, and the implications for reproducibility and data sharing.
4 articles • Protocols for single-cell protein detection
Protocols and optimization strategies for single-cell protein detection, staining optimization, and multi-omics workflows using antibody-oligonucleotide conjugates.
Exploring the potential and challenges of universal antibody barcoding with oligonucleotides for research applications, and the implications for reproducibility and data sharing.
Protocols and optimization strategies for single-cell protein detection, including staining conditions, buffer optimization, and workflow considerations for multiomics applications.
Optimization of labeling ratios for enhanced performance in single-cell applications. Finding the optimal balance between signal strength and specificity in multi-omics workflows.
Survey of multiplexed techniques and applications enabled by AOCs, from proximity ligation assays to advanced imaging methods and single-cell analysis.
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