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AOC Custom Services

Antibody-oligo conjugates (AOCs) are ideal for:

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Proteome analysis

Analyse 1,000s of proteins from of a single sample, whilst simultaneously detecting lowly expressed proteins


 
​​school of fish in water
Eliminating reagent waste

It is no longer necessary to buy standard pack sizes of 100µg, we manufacture AOCs requiring only 20µg of starting material.


 
Reducing reagent costs

AOCs are highly sensitive therefore requiring less reagents for each experiment



Discover A New Approach to Manufacturing 


AOCs are highly tunable, sensitive reagents, thus requiring a new approach to manufacturing to ensure:

  • Scale - manufactured at the µg scale rather than mg/g.


  • Flexibility - have the option​ to select the intermediate reagents (antibody/oligo) for their research needs.


  • Batch consistency - quantitative QC release criteria to deliver a high level of confidence in the product. 

Scale

We manufacture AOCs ~20µg+

Fine Tuning Your AOC

Custom DoL for optimal assay performance

QC Innovation

Quantitative release criteria provides the confidence you need

Time

Product ready to ship within  days    .

AbOliGo Conjugation Capabilities​


AbOliGO AOC demonstrating the light chains (LC) and heavy chains  (HC) are labeled with either 1, 2 or 3 oligos (reducing gel).

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AbOliGo - fast, reproducible, antibody conjugates for all 


Getting Started with our custom oligo service is a breeze, thanks to our well-structured and comprehensive on-boarding process.



Why Choose AbOliGo for Antibody-Oligonucleotide Conjugation? 

We have optimized and crafted our conjugation processes to generate tailor designed AOCs to meet your requirements. Our focus on batch-to-batch consistency ensures that our conjugates exhibit the same performance across multiple batches, maximizing the reliability of your results. 


Innovative Conjugation Expertise

Our team brings decades of experience in fine tuning conjugates, offering:

  • Covalent coupling strategies for diverse applications.
  • Customization to target amine or sulfhydryl groups, ensuring compatibility with your experimental goals.
  • Rigorous quality control.

 

Flexible Antibody & Oligonucleotide Pairing 

We have experience of conjugating antibodies covering a large number of host species (monoclonal or polyclonal) and isotypes. 

 

Conjugate Scale and Fast Turnaround Times 

As a result of scaling down AbOliGo’s conjugation processes we generate AOCs down to 20µg with a turnaround of days. 

 

Conjugation Process 

At AbOliGo, we follow a robust, step-by-step conjugation workflow that emphasizes precision and quality at each stage 


Project workflow 

Stage 1 Consultation and Design

20%


Our team collaborates with you to clearly define: 

  1. The scope of the project. 
  2. Target product profile, QC release criteria and timeline deliverables.  


Stage 2 Antibody & Oligo Selection

40%


We provide flexible options:

  1. Customer sends their pre-selected antibodies and oligos to us. 
  2. We are happy to purchase the antibodies/oligos on behalf of the customer.

 

Stage 3 Conjugation & Purification

60%

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Using cutting-edge chemistry and purification methods, we produce high-purity AOCs that meet stringent quality standards. 

  

Stage 4 Quality Control & Validation

80%


Conjugates validated and QC released using proprietary approaches.


Stage 5 AOC dispatched

100%

 

Partner With Us 

 Ready to start your project? Connect with us to learn how our custom AOC services can support your research. 

Contact us to discuss your AOC requirements


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