We all want more data! Multiplex Assays are accelerating scientific discovery. We also need the sensitivity to detect low abundance proteins in tiny samples (and even single cells)!
The quest to understand proteins has long relied on antibodies as our primary investigative tools. But what if we could supercharge these trusted reagents?
🔬 Antibody-Oligonucleotide Conjugates (AOCs): The Workhorse of Multiplex Assays
AOCs are the perfect reagent for studying proteins! They are revolutionizing multiplex assays by combining the target-specific binding of antibodies with the unique properties of oligonucleotides - amplification and molecular barcoding. However, as multiplexing evolves, the scientific community is facing new challenges, the biggest being the need for flexibility and consistency when working with AOCs.
The Need for Flexibility in Multiplex Experiments
The increasing popularity of multiplexing means scientists are integrating multiple platforms into their experiments, for example:
🧬 Spatial biology for tissue mapping.
🧫 Single-cell analysis for cellular heterogeneity studies.
📊 Flow cytometry for immune profiling.
Each instrument often requires AOCs tailored to specific protocols and detection systems, which raises a critical question: how can scientists ensure the same set of antibodies can be reliably used across different instruments?
🏭 AbOliGo – fast, reproducible AOCs for all
To meet the growing demand for flexible and consistent AOCs, AbOliGO is developing procedures to offer small-scale manufacturing of antibody-oligonucleotide conjugates with a focus on flexibility, reproducibility, and speed.
By providing quantitative quality control (QC) for each batch, AbOliGO will ensure researchers trust the performance of their AOCs across multiple platforms.
💡 Should We Barcode All Research Antibodies?
With over seven million research antibodies available, the idea of barcoding all of them with oligos might seem ambitious. However, as multiplex technologies continue to advance, the demand for ready-to-use, reliable AOCs will only grow.
By embracing small-scale, on-demand manufacturing and quantitative QC processes, the scientific community can ensure that these indispensable tools keep pace with the needs of modern research.
The future of multiplex assays lies in flexibility and reproducibility of AOCs.
Learn more at www.aboligo.com